John A Kellum Selected Research

Hemofiltration

1/2016	Modeling and Hemofiltration Treatment of Acute Inflammation.
9/2013	Blood purification and mortality in sepsis: a meta-analysis of randomized trials.
6/2012	High-volume hemofiltration in the intensive care unit: a blood purification therapy.
1/2011	Clinical review: blood purification for sepsis.
10/2002	Effect of hemofiltration filter adsorption on circulating IL-6 levels in septic rats.
2/2002	Pro/con clinical debate: is high-volume hemofiltration beneficial in the treatment of septic shock?

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John A Kellum Research Topics

Disease

189	Acute Kidney Injury (Acute Renal Failure) 05/2024 - 01/2002
114	Sepsis (Septicemia) 03/2024 - 02/2002
87	Critical Illness (Critically Ill) 11/2023 - 01/2002
32	Septic Shock (Toxic Shock Syndrome) 03/2024 - 02/2002
31	Inflammation (Inflammations) 01/2023 - 01/2003
27	Kidney Diseases (Kidney Disease) 03/2024 - 03/2013
18	Infections 05/2024 - 08/2007
15	Acidosis 01/2023 - 02/2002
13	Pneumonia (Pneumonitis) 01/2022 - 04/2007
11	Hypotension (Low Blood Pressure) 01/2023 - 01/2004
10	COVID-19 11/2023 - 10/2020
10	Heart Failure 10/2020 - 10/2002
9	Chronic Renal Insufficiency 12/2023 - 01/2010
9	Oliguria 01/2023 - 04/2008
9	Renal Insufficiency (Renal Failure) 01/2021 - 12/2003
8	Chronic Kidney Failure (Chronic Renal Failure) 03/2024 - 01/2003
8	Fibrosis (Cirrhosis) 01/2023 - 01/2010
7	Reperfusion Injury 07/2023 - 07/2010
7	Brain Death (Brain Dead) 01/2019 - 01/2004
6	Multiple Organ Failure (MODS) 11/2023 - 10/2002
6	Endotoxemia 11/2023 - 03/2004
5	Ischemia 12/2022 - 01/2010
5	Shock 10/2022 - 06/2002
5	Hemorrhage 10/2020 - 09/2007
4	Drug-Related Side Effects and Adverse Reactions 05/2024 - 11/2016
4	Body Weight (Weight, Body) 11/2023 - 07/2008
4	Thrombocytopenia (Thrombopenia) 04/2023 - 10/2002
4	Peritonitis 01/2023 - 12/2012
4	Acute Disease 01/2022 - 01/2016
3	Hyperglycemia 12/2023 - 01/2020
3	Hypertension (High Blood Pressure) 12/2023 - 01/2013
3	Proteinuria 11/2023 - 01/2013
3	Cardiovascular Diseases (Cardiovascular Disease) 03/2023 - 06/2008
3	Hypercapnia 10/2019 - 05/2007
3	Azotemia 10/2019 - 01/2016

Drug/Important Bio-Agent (IBA)

86	Biomarkers (Surrogate Marker)IBA 12/2023 - 12/2005
49	CreatinineIBA 01/2022 - 12/2005
26	CytokinesIBA 12/2022 - 12/2002
21	Insulin-Like Growth Factor Binding ProteinsIBA 03/2024 - 01/2014
18	Interleukin-6 (Interleukin 6)IBA 01/2019 - 01/2004
10	Anti-Bacterial Agents (Antibiotics)IBA 05/2024 - 02/2012
10	Tissue Inhibitor of MetalloproteinasesIBA 03/2024 - 04/2014
10	AcidsIBA 01/2019 - 02/2002
10	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2017 - 01/2004
9	EndotoxinsIBA 11/2023 - 05/2018
9	Lactic Acid (Lactate)FDA LinkGeneric 09/2019 - 05/2004
9	Interleukin-10 (Interleukin 10)IBA 10/2014 - 01/2004
8	DiureticsIBA 01/2023 - 08/2004
8	AlbuminsIBA 01/2023 - 01/2007
8	Tissue Inhibitor of Metalloproteinase-2IBA 11/2020 - 01/2014
7	Urea (Carbamide)FDA LinkGeneric 01/2023 - 09/2008
7	Saline SolutionIBA 08/2021 - 02/2002
7	ElectrolytesIBA 01/2016 - 02/2002
6	Vancomycin FDA LinkGeneric 05/2024 - 06/2015
6	ChemokinesIBA 04/2024 - 07/2014
6	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2003
6	Aluminum Oxide (Sapphire)IBA 10/2021 - 02/2013
6	SolutionsIBA 08/2021 - 02/2002
6	fibrin fragment D (D-dimer)IBA 01/2019 - 05/2009
6	ChloridesIBA 01/2019 - 02/2006
6	ProcalcitoninIBA 07/2018 - 07/2008
5	LigandsIBA 04/2024 - 01/2021
5	Alkaline PhosphataseIBA 03/2024 - 09/2016
5	Polymyxin B (Aerosporin)FDA LinkGeneric 11/2023 - 01/2007
5	Folic Acid (Vitamin M)FDA LinkGeneric 01/2023 - 09/2011
5	SodiumIBA 01/2021 - 01/2010
5	Bicarbonates (Hydrogen Carbonate)IBA 09/2019 - 03/2015
5	Lipocalin-2IBA 01/2019 - 09/2011
4	LipopolysaccharidesIBA 11/2023 - 12/2002
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2021 - 10/2014
4	Carrier Proteins (Binding Protein)IBA 01/2021 - 01/2018
4	AntithrombinsIBA 09/2012 - 10/2010
3	Glutamine (L-Glutamine)FDA Link 11/2023 - 04/2013
3	Phosphates (Orthophosphate)IBA 01/2023 - 10/2009
3	IronIBA 01/2023 - 01/2019
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023 - 02/2014
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2022 - 10/2006
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 10/2022 - 06/2002
3	Insulin (Novolin)FDA Link 01/2021 - 01/2018
3	Heparin (Liquaemin)FDA LinkGeneric 10/2020 - 01/2011
3	Citric Acid (Citrate)FDA LinkGeneric 10/2020 - 09/2007
3	Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric 11/2019 - 05/2019

Therapy/Procedure

67	Renal Replacement Therapy (Therapies, Renal Replacement) 04/2023 - 11/2002
66	Therapeutics 10/2023 - 01/2002
25	Resuscitation 03/2024 - 02/2002
23	Continuous Renal Replacement Therapy 01/2022 - 01/2002
13	Critical Care (Surgical Intensive Care) 10/2022 - 06/2002
12	Artificial Respiration (Mechanical Ventilation) 01/2023 - 08/2005
12	Renal Dialysis (Hemodialysis) 10/2020 - 01/2002
11	Ligation 12/2023 - 01/2004
11	Punctures 12/2023 - 01/2004
9	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2020 - 10/2002
8	Length of Stay 11/2023 - 01/2006
6	Liver Transplantation 01/2020 - 07/2010
6	Early Goal-Directed Therapy 01/2019 - 04/2008
6	Hemofiltration 01/2016 - 02/2002
4	Fluid Therapy (Oral Rehydration Therapy) 01/2019 - 12/2002
4	Transplantation 08/2009 - 01/2004
3	Plasma Exchange 04/2023 - 10/2002
3	Precision Medicine 04/2021 - 10/2017